How often will the variable values change and be updated?
From the datasheets, EEPROM has a finite number of write cycles.
Number of Total Erase/Write Cycles before Refresh(2) is typically 10 million erase/write cycles.
At a variable values update rate of once per second that equates to around 115 days continuous operation. So if infrequent use, then will likely last some years.
If trying to retain values that can be changing 100 times a second, then your may just incur EEPROM errors after around 24 hours continuous operation
Keep in mind the 10 Million write cyclkes is typical and some on this forum have deliberate done tests and achieved far better results but no guarantees apply.